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  5. Thermo Scientific™ Harvest RC Chromatographic Clarifier

Thermo Scientific™ Harvest RC Chromatographic Clarifier

Product Code. 17577096 Shop All Thermo Scientific Products
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Flow Rate:
0.594 gal./min.
Closure Type:
1 1/2 in. Sanitary Connectors
Quantity:
1 Ea.
Unit Size:
Each
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Product Code. Flow Rate Closure Type Quantity Unit Size
17577096 0.594 gal./min. 1 1/2 in. Sanitary Connectors 1 Ea. Each
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Product Code. 17577096 Supplier Thermo Scientific™ Supplier No. 7100236846
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Description

The Harvest RC Chromatographic Clarifier is a single‐use, single‐stage option for efficient harvesting and clarification of modern cell cultures. It streamlines processing with fewer steps, higher yield, and reduced production time and cost.

Harvest RC Chromatographic Clarifier is a single-use, single-stage solution for efficient cell culture harvest and clarification. Using synthetic chromatographic media, it combines harvest and clarification into one step, improving downstream performance. It enables higher product recovery, consistent effluent, and predictable scalability while reducing process time and complexity. Available in multiple sizes for seamless scale-up from bench to production.

  • Simplification of high cell density cell culture fluid clarification unit operations.
  • Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid.
  • Optimized for PCV high density CHO cell culture (5-8% PCV)
  • Replacement of primary, secondary and guard membrane clarification stages.
  • Typical product recovery of 95+% (capsules)
  • Synthetic chromatographic harvest media with chemically defined extractables.
  • Predictable scaling from discovery to manufacturing.
  • Lower total cost of manufacturing compared to centrifugation and depth filtration.
  • Lower consumption of buffer and water compared to depth filtration.
  • Capsules fit into laboratory to manufacturing scale workflows.

Specifications

Autoclavable Not Autoclavable
Basis Weight 21.61 oz.
Bed Volume 551.16 oz.
Cap Material Glass Filled Polypropylene, Polycarbonate, Polypropylene, Silicone, Thermoplastic Elastomer TPE
Connectors Sanitary Connectors
Disposable Single-use
Filter Type Single-use
Material Glass-filled Polypropylene, Polycarbonate, Polypropylene, Silicone, TPE
Material (Membrane) PES
Pore Size 0.2 μm
Filtration Area 17.378 ft.²
Filtration Speed 0.594 gal./min.
Flow Rate 0.594 gal./min.
For Use With (Application) Harvest and Clarification
Inlet Connection (English) Sanitary Connectors
Max. Pressure 49 lb./in.
Quantity 1 Ea.
Temperature (English) Max. 104°F
Temperature (Metric) Max 40°C
Volume (English) 551.16 oz.
Volume (Metric) 16.3 L
Waterflow Rate 0.594 gal./min.
Height (English) 8.74 in.
Height (Metric) 22.2 cm
Diameter (English) 17.8 in.
Diameter (Metric) 45.2 cm
Weight (English) 21.61 oz.
Weight (Metric) 9.8 kg
Closure Type 1 1/2 in. Sanitary Connectors
Gasket Silicone
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