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Cytiva HiTrap™ MabSelect™ Prepacked Columns

Product Code. 10359534 Shop All Cytiva Products
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Quantity:
1 x 5 mL
5 x 1 mL
5 x 5 mL
Product Line:
MabSelect
MabSelect™ Xtra
Förpackningsstorlek
Each
Pack of 5
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Produktkode 10359534

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Use these columns in small-scale MAb purification in a continuous bioprocess. Cytiva Life Sciences™ HiTrap™ MabSelect™ Prepacked Columns for fast purification of monoclonal antibodies (Mabs) from large sample volumes

Prepacked HiTrap columns for process development, screening of purification conditions, and small-scale purification of Mabs. MabSelect media are suited for the high flowrates and pressures required when scaling up.

  • Oriented coupling of recombinant Protein A ligand to the agarose matrix via an engineered C-terminal cysteine increases IgG binding capacity over other protein A media
  • High capacity, low ligand leakage, and high-flow base matrix allow purification of Mabs at process scale
  • Fewer regulatory concerns due to the total absence of mammalian culture in the ligand production and purification
  • Designed for use with a syringe, a peristaltic pump, or a chromatography system

MabSelect

  • Allows at least five times higher flowrates than conventional cross-linked agarose of similar porosity
  • Recombinant Protein A ligand promotes specificity of binding to Fc region of IgG; permits one-step purification
MabSelect Xtra™
  • Same recombinant protein A ligand as MabSelect, but with a smaller particle size and greater porosity, for increased dynamic binding capacity
  • Allows binding from samples with high expression levels of the monoclonal antibody
  • Lowers overall production cost due to the possibility of processing concentrated feedstocks in fewer batches
MabSelect SuRe™ (Superior Resistance)
  • Akali-tolerant protein A-derived ligand allows the use of up to 0.5M NaOH for cleaning-in-place (CIP)
  • Permits significant cost savings and extension of cycles in regular production

TRUSTED_SUSTAINABILITY

Tekniske data

Product Type Pre-packed Columns
Product Line MabSelect
Binding Capacity ∼30 mg/mL Human lgG at 2.4 min. residence time
Diameter (Metric) Inner Column 0.7 cm
Diameter (English) Inner Column 0.27 in.
Flow Rate <4 mL/min.
Volume (Metric) Bed 1 mL
For Use With (Application) For fast purification of monoclonal antibodies from large sample volumes, Protein Purification
Description HiTrap MabSelect columns are prepacked with MabSelect, a BioProcess resin for capturing of mAbs from large sample volumes.
Sample Volume 1 mL
Storage Buffer 20% Ethanol
Content And Storage 4°C to 30°C
Quantity 5 x 1 mL
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Produktidentifikator
  • HiTrap MabSelect, 1 ml, 5 x 1 ml
Signalord
  • Warning
Farekategori
  • Flammable liquid Category 3
Faresætning
  • H226-Flammable liquid and vapour.
Sikkerhedssætning
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P235-Keep cool.
  • P501-Dispose of contents/container to .
Supplerende oplysninger
  • MIXTURE LIST-Contains : ethanol
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