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Invitrogen™ Human ATMIN (aa 72-167) Control Fragment Recombinant Protein

Product Code. 30208363
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30208363

Brand: Invitrogen™ RP106587

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This item is not returnable. View return policy

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65908 (PA5-65908. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51. ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects. It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number O43313
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 23300
Name Human ATMIN (aa 72-167) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias ASCIZ; ATM INteracting protein; ATM interactor; ATM/ATR-substrate CHEK2-interacting zinc finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATM/ATR-Substrate Chk2-Interacting Zn++-finger protein; ATM/ATR-Substrate Chk2-Interacting Zn2+-finger protein; atmin; gpg6; KIAA0431; mKIAA0431; RGD1305781; Zinc finger protein 822; ZNF822
Common Name ATMIN
Gene Symbol ATMIN
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SVSELSRAVRTNILCTVRGCGKILPNSPALNMHLVKSHRLQDGIVNPTIRKDLKTGPKFYCCPIEGCPRGPERPFSQFSLVKQHFMKMHAEKKHKC
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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