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Proteintech Human BAFF ELISA Kit

Code produit. 17254876 Tous les produits Proteintech Produits
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Gene ID (Entrez):
10673
Conditionnement:
96 reactions
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Code produit. 17254876

Marque: Proteintech KE0021596T

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Description

BAFF, or B cell-activating factor, also known as B lymphocyte stimulator (BlyS; trademark of Human Genome Sciences, Rockville, MD), TALL‐1, THANK, and TNFSF13B, is a member of the tumor necrosis factor (TNF) superfamily and is best known for its role in the survival and maturation of B cells.

The full-length molecule of BAFF is a 285-amino acid (285 aa) peptide with 2 potential N-glycosylation sites at residues 124 and 242. Cleavage downstream from aa 124 releases a first form of nonglycosylated BAFF, and possibly a second form glycosylated at aa 242. A 152-amino acid form can also be shed from the membrane and is detectable in human serum. Studies on BAFF transgenic mice and patients with rheumatoid diseases indicate that overexpression of BAFF is linked to the development of autoimmune pathology. BAFF expression was detectable in heart, skeletal muscle, pancreas, kidney, skin with adipose tissue, and liver at similar levels as in the CNS.

Spécification

Gene ID (Entrez) 10673

Sécurité et traitement

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Identifiant produit
  • 96RXN Human BAFF ELISA Kit
 Mention d'avertissement
  • Warning
 Catégorie de danger
  • Serious eye damage/eye irritation Category 1
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Mention de danger
  • H302-Harmful if swallowed.
  • H315-Causes skin irritation.
  • H318-Causes serious eye damage.
  • H319-Causes serious eye irritation.
  • H332-Harmful if inhaled.
  • H335-May cause respiratory irritation.
 Conseils de prudence
  • P201-Obtain special instructions before use.
  • P202-Do not handle until all safety precautions have been read and understood.
  • P234-Keep only in original container.
  • P264-Wash skin thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P273-Avoid release to the environment.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P330-Rinse mouth.
  • P362-Take off contaminated clothing.
  • P405-Store locked up.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Informations supplémentaires
  • MIXTURE LIST-Contains : Sulphuric Acid, Tetramethylbenzidine
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