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Gibco™ Human BMP-4 Recombinant Protein, PeproTech®

Product Code. 17810473
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1 μg
10 x 100 μg
100 μg
5 μg
5 x 100 μg
50 μg
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1mg
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500µg
50µg
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Product Code. Quantity unitSize
17810473 50 μg 50µg
17800943 100 μg 100µg
17829992 10 x 100 μg 1mg
30088425 10 x 100 μg Pack of 10
17821043 1 μg 1µg
30089392 5 x 100 μg Pack of 5
17861503 5 x 100 μg 500µg
17811153 5 μg 5µg
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Product Code. 17810473 Supplier Gibco™ Supplier No. 1200550UG

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701.10 EUR valid until 2026-08-31
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This item is not returnable. View return policy

Description

Recombinant Protein

120-05-1MG will be provided as 10 x 100 μg (120-05-100UG). 120-05-500UG will be provided as 5 x 100 μg (120-05-100UG). Recombinant Human BMP-4, expressed in HeLa cells, is a 25.6 kDa homodimeric glycoprotein. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P12644
For Use With (Application) Control, Western Blot Control, Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 652
Molecular Weight (g/mol) 25.6 kDa
Name Human BMP-4
Purification Method Purified
Quantity 50 μg
Source HeLa cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
Common Name BMP4
Gene Symbol BMP4
Biological Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR
Content And Storage -20°C
Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 2-8 ng/ml.
Expression System HeLa cells
Form Lyophilized
Purity or Quality Grade ≥ 97% by SDS-PAGE gel and HPLC analyses.
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