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Gibco™ Human BMP-5 Recombinant Protein, PeproTech®

Product Code. 17880393
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Quantity:
10 μg
100 μg
2 μg
2 x 250 μg
250 μg
4 x 250 μg
50 μg
Unit Size:
100µg
10µg
1mg
250µg
2µg
500µg
50µg
Pack of 2
Pack of 4
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Product Code. 17880393

Brand: Gibco™ 12039100UG

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This item is not returnable. View return policy

Description

Recombinant Protein

120-39-1MG will be provided as 4 x 250 μg (120-39-250UG). 120-39-500UG will be provided as 2 x 250 μg (120-39-250UG). Recombinant Human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lungs and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P22003
For Use With (Application) Control, Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 653
Molecular Weight (g/mol) 31.2 kDa
Name Human BMP-5
Purification Method Purified
Quantity 100 μg
Source CHO cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias AU023399; BMP; BMP 5; Bmp5; BMP-5; bone morphogenenic protein-5; Bone morphogenetic protein; bone morphogenetic protein 5; MGC34244; se; short ear
Common Name BMP5
Gene Symbol Bmp5
Biological Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 ug/ml
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence AANKRKNQNR NKSSSHQDSS RMSSVGDYNT SEQKQACKKH ELYVSFRDLG WQDWIIAPEG YAAFYCDGEC SFPLNAHMNA TNHAIVQTLV HLMFPDHVPK PCCAPTKLNA ISVLYFDDSS NVILKKYRNM VVRSCGCH
Content And Storage -20°C
Activity Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.0 ug/ml.
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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