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Invitrogen™ Human Claudin 19 (aa 37-71) Control Fragment Recombinant Protein

Product Code. 30199083
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30199083

Brand: Invitrogen™ RP109977

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144714 (PA5-144714. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

The product of this gene belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Defects in this gene are the cause of hypomagnesemia renal with ocular involvement (HOMGO). HOMGO is a progressive renal disease characterized by primary renal magnesium wasting with hypomagnesemia, hypercalciuria and nephrocalcinosis associated with severe ocular abnormalities such as bilateral chorioretinal scars, macular colobomata, significant myopia and nystagmus. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jun 2010].
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8N6F1
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 149461
Name Human Claudin 19 (aa 37-71) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias claudin 19; claudin-19; Cldn19; HOMG5
Common Name Claudin 19
Gene Symbol CLDN19
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence GDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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