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Invitrogen™ Human Cystatin C (aa 27-146) Control Fragment Recombinant Protein

Product Code. 30201346
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30201346

Brand: Invitrogen™ RP90035

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (72%), Rat (72%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-110779 (PA5-110779. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Cystatin C, a member of the type 2 cystatin superfamily, is a potent inhibitor of cysteine proteinases, both endogenous (lysosomal cathepsins), and pathogenic. Cystatin C is a 13 kDa secreted protein which is found in high concentrations in biological fluids and is thought to be expressed by all human nucleated cells. Changes in Cystatin C have been documented in a number of cardiovascular diseases, including atherosclerosis, amyloid angiopathy and myocardial infarction. Its low molecular weight also means that Cystatin C can be used as a marker of renal failure.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P01034
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 1471
Name Human Cystatin C (aa 27-146) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias AD8; ARMD11; bA218C14.4 (cystatin C); CST3; CYSC; cystatin; cystatin 3; cystatin C; cystatin C (amyloid angiopathy and cerebral hemorrhage); Cystatin C (cysteine proteinase inhibitor); Cystatin3; cystatin-3; CystatinC; Cystatin-C; epididymis secretory protein Li 2; fb51d07; Gamma-trace; HEL-S-2; MGC117328; neuroendocrine basic polypeptide; OTTHUMP00000030440; OTTHUMP00000164181; OTTHUMP00000164182; OTTMUSP00000016736; Post-gamma-globulin; RP23-250M11.9; wu:fb24g06; wu:fb51d07; wu:fc55f03; zgc:136227
Common Name Cystatin C
Gene Symbol Cst3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEYNKASNDMYHSRALQVVRARKQIVAGVNYFLDVELGRTTCTKTQPNLDNCPFHDQPHLKRKAFCSFQIYAVPWQGTMTLSKSTCQDA
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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