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Invitrogen™ Human Fibrillin 1 (aa 2685-2833) Control Fragment Recombinant Protein

Product Code. 30199284
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30199284

Brand: Invitrogen™ RP90823

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82598 (PA5-82598. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P35555
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 2200
Name Human Fibrillin 1 (aa 2685-2833) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias ACMICD; AI536462; Asprosin; B430209H23; ECTOL1; FBN; Fbn1; Fbn-1; Fib-1; fibrillin 1; fibrillin 15; fibrillin-1; GPHYSD2; MASS; MFLS; MFS1; MP340; OCTD; putative; SGS; SSKS; tight skin; Tsk; WMS; WMS2
Common Name Fibrillin 1
Gene Symbol FBN1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence HCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECKINGYPKRGRKRRSTNETDASNIEDQSETEANVSLASWDVEKTAIFAFNISHVSNKVRILELLPALTTLTNHNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVAGTYSLQISS
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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