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  4. Invitrogen™ Human IL-13 Recombinant Protein

Invitrogen™ Human IL-13 Recombinant Protein

Product Code. 17975931
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Quantity:
1 mg
100 μg
5 μg
Unit Size:
100µg
1mg
5µg
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Product Code. 17975931

Brand: Invitrogen™ RP88070

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This item is not returnable. View return policy

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. Reconstitute with sterile deionized water to 0.1 mg/mL. Concentration is measured by UV.

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P35225
Concentration 0.25 mg/mL
For Use With (Application) Control, Bioactivity
Format Lyophilized
Formulation PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 3596
Molecular Weight (g/mol) 12.35 kDa
Name Human IL-13
pH Range 7.4
Purification Method Purified
Quantity 1 mg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <0.01 EU/μg
Gene Alias ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Common Name IL-13
Gene Symbol Il13
Biological Activity Measured in a cell proliferation assay using TF1 human erythroleukemic cells (Kitamura, T. et al. 1989, J. Cell Physiol. 140:323.). The ED50 for this effect is typically 0.5-3 ng/mL
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence Human IL13, amino acids Met1-Asn132 (Accession # AAK53823.1)
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Activity Measured in a cell proliferation assay using TF1 human erythroleukemic cells (Kitamura, T. et al. 1989, J. Cell Physiol. 140:323.). The ED50 for this effect is typically 0.5-3 ng/mL.
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥95% as determined by SDS-PAGE. ≥95% as determined by SEC-HPLC
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