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  4. Invitrogen™ Human IL-13 Recombinant Protein

Invitrogen™ Human IL-13 Recombinant Protein

Product Code. 16635444
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Quantity:
5 μg
5 x 50 μg
Unit Size:
5µg
Pack of 5
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Product Code. 16635444

Brand: Invitrogen™ A42526

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Description

Recombinant Protein

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P35225
For Use With (Application) Control, Bioactivity, Immunohistochemistry, Western Blot
Formulation PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 3596
Molecular Weight (g/mol) 12.5 kDa
Name Human IL-13
pH Range 7.4
Purification Method Purified
Quantity 5 μg
Source CHO cells
Storage Requirements -20°C or -80°C if preferred
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias ALRH; ALRH antibody; BHR1; il 13; Il13; Il-13; IL-13; cytokine; ILN; Interleukin; interleukin 13; Interleukin13; interleukin-13; interleukin-13 precursor; L13; MGC116786; MGC116788; MGC116789; NC30; NC30 antibody; P600; P600 antibody; T-cell activation protein P600
Common Name IL-13
Gene Symbol Il13
Biological Activity Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.5-3 ng/mL
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag Untagged
Sequence Human IL-13, amino acids Met1-Asn132 (Accession # AAK53823.1)
Content And Storage Includes 1 vial of lyophilized protein. Store at -20 °C.
Activity Measured in a cell proliferation assay using TF1 human erythroleukemic cells. The ED50 for this effect is typically 0.5-3 ng/mL.
Endotoxin Level < 1 EU/μg
Expression System CHO cells
Protein Family Cytokines & Receptors
Form Lyophilized
Protein Subtype Interleukins
Research Category Immunology, Inflammation, Signal Transduction
Purity or Quality Grade >92% by SDS-PAGE
Protein interleukin 13
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