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Invitrogen™ Human MYO18A (aa 1340-1436) Control Fragment Recombinant Protein

Product Code. 30208508
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30208508

Brand: Invitrogen™ RP92099

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54041 (PA5-54041. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q92614
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 399687
Name Human MYO18A (aa 1340-1436) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias CD245; KIAA0216; MAJN; molecule associated with JAK3 N-terminus; Myo18a; MyoPDZ; myosin 18 A; myosin containing a PDZ domain; myosin containing PDZ domain; myosin XVIIIa; myosin XVIIIb; myosin-XVIIIa; MysPDZ; SP-A receptor subunit SP-R210 alphaS; SPR210; SP-R210; Surfactant protein receptor SP-R210; Unconventional myosin-XVIIIa
Common Name MYO18A
Gene Symbol MYO18A
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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