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  4. Invitrogen™ Human Nectin-2 (CD112) Fc Chimera Recombinant Protein

Invitrogen™ Human Nectin-2 (CD112) Fc Chimera Recombinant Protein

Product Code. 17916121
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
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17916121 1 mg 1mg
17926341 100 μg 100µg
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Product Code. 17916121 Supplier Invitrogen™ Supplier No. RP87967
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Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (1493 μL) be added to the vial to prepare a stock solution of 0.67 mg/mL. Concentration is measured by UV.

This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q92692
Concentration 0.25 mg/mL
For Use With (Application) Control, ELISA Standard, Binding Assay
Format Lyophilized
Formulation PBS with 5% mannitol, 5% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Gene ID (Entrez) 5819
Molecular Weight (g/mol) 70-80 kDa
Name Human Nectin-2 (CD112) Fc Chimera
pH Range 7.4
Purification Method Purified
Quantity 1 mg
Storage Requirements -20°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Endotoxin Concentration <1.0 EU/μg
Gene Alias AI325026; AI987993; CD112; herpes virus entry mediator B; Herpesvirus entry mediator B; herpesvirus entry protein B; hveB; mHveB; MPH; Murine herpes virus entry protein B; murine herpesvirus entry protein B; nectin cell adhesion molecule 2; Nectin2; Nectin-2; Poliovirus receptor homolog; poliovirus receptor related 2; poliovirus receptor-like 2; poliovirus receptor-related 2; poliovirus receptor-related 2 (herpesvirus entry mediator B); poliovirus receptor-related protein 2; poliovirus sensitivity; PRR2; Pvr; Pvrl2; PVRR2; Pvs
Common Name Nectin 2
Gene Symbol NECTIN2
Biological Activity 1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μL/well) can bind human CD112 with a linear range of 6.4-800 ng/mL 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag) (at 2 μg/ml (100 μL/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL)
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Protein Tag Fc-tag
Sequence Human CD112, amino acids Met1-Leu360 (Accession # NP_002847.1) with a C-terminal human IgG1 Fc region
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Activity 1. Measured by its binding ability in a functional ELISA. Immobilized human CD226 at 2 μg/ml (100 μL/well) can bind human CD112 with a linear range of 6.4-800 ng/mL. 2. Immobilized PVRIG Protein, Cynomolgus, Rhesus, Recombinant (His Tag) at 2 μg/ml (100 μL/well) can bind Nectin-2 Protein, Human, Recombinant (hFc Tag), the EC50 of Nectin-2 Protein, Human, Recombinant (hFc Tag)is 0.2-1.2 ng/mL.
Expression System HEK293 cells
Form Lyophilized
Purity or Quality Grade >95% as determined by SDS-PAGE.
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