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Abnova™ Human PLG native Protein from human plasma

Product Code. 16068096
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1 mg
Unit Size:
1mg
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Product Code. 16068096 Supplier Abnova™ Supplier No. P4958.1mg

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Description

Used for Func, SDS-PAGE

Plasminogen (PLG) is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase (PLAU; MIM 191840) and tissue plasminogen activator (PLAT; MIM 173370). The main function of plasmin is to dissolve fibrin (see, e.g., FGA, MIM 134820) clots. Plasmin, like trypsin, belongs to the family of serine proteinases (Miyata et al., 1982 [PubMed 6216475]; Forsgren et al., 1987 [PubMed 3030813]).[supplied by OMIM]

Specifications

Concentration 4.1 mg/mL
For Use With (Application) Functional Study, SDS-PAGE
Formulation In 0.1M Hepes, 0.1M NaCl, pH 7.4
Gene ID (Entrez) 5340
Molecular Weight (g/mol) 92kDa
Name PLG (Human) Native Protein
Preparation Method Native protein purified from human plasma
Purification Method Lysine sepharose chromatography
Quantity 1 mg
Storage Requirements Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Regulatory Status RUO
Gene Alias DKFZp779M0222
Common Name PLG
Gene Symbol PLG
Biological Activity No plasmin activity is detected with chromogenic substrate S-2251.
> 98% conversion to plasmin is observed upon activation with uPA.
Species Human
Protein Tag None
Expression System Native protein purified from human plasma
Form Liquid
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