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Gibco™ Human R-Spondin 1 Recombinant Protein, PeproTech®

Product Code. 30088098
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Quantity:
100 μg
2 x 500 μg
20 μg
250 μg
5 μg
500 μg
Unit Size:
100µg
20µg
250µg
500µg
5µg
Pack of 2
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Product Code. Quantity unitSize
30088098 2 x 500 μg Pack of 2
17889922 100 μg 100µg
17871473 20 μg 20µg
17880303 250 μg 250µg
17890123 500 μg 500µg
17850573 5 μg 5µg
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Product Code. 30088098 Supplier Gibco™ Supplier No. 1203801M
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Description

Recombinant Protein

120-38-1MG will be provided as 2 x 500 μg (120-38-500UG). Recombinant Human R-Spondin-1 is a 26.7 kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis.

This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q2MKA7
For Use With (Application) Control, Bioactivity
Formulation Protein with no preservative
Gene ID (Entrez) 284654
Molecular Weight (g/mol) 26.7 kDa
Name Human R-Spondin 1
Purification Method Purified
Quantity 2 x 500 μg
Source CHO cells
Storage Requirements -20°C
Regulatory Status RUO
Endotoxin Concentration <1 EU/μg
Gene Alias CRISTIN3; cristin-3; cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; RGD1565558; Roof plate-specific spondin-1; RP11-566C13.1; RSPO; RSPO1; Rspondin; R-spondin; R-spondin 1; R-spondin homolog; R-spondin homolog (Xenopus laevis); R-spondin-1; thrombospondin type 1 domain containing gene Rspondin
Common Name RSPO1
Gene Symbol RSPO1
Biological Activity R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml
Product Type Protein
Conjugate Unconjugated
Recombinant Recombinant
Sequence SRGIKGKRQR RISAEGSQAC AKGCELCSEV NGCLKCSPKL FILLERNDIR QVGVCLPSCP PGYFDARNPD MNKCIKCKIE HCEACFSHNF CTKCKEGLYL HKGRCYPACP EGSSAANGTM ECSSPAQCEM SEWSPWGPCS KKQQLCGFRR GSEERTRRVL HAPVGDHAAC SDTKETRRCT VRRVPCPEGQ KRRKGGQGRR ENANRNLARK ESKEAGAGSR RRKGQQQQQQ QGTVGPLTSA GPA
Content And Storage -20°C
Activity R-Spondin-1 enhances BMP-2-mediated differentiation of MC3T3-E1 cells. The expected ED50 is 1.0-3.0 ug/ml.
Expression System CHO cells
Form Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
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