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STEMCELL Technologies Human Recombinant BMP-2

Product Code. 17139321
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100 μg
1000 μg
50 μg
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100µg
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Product Code. 17139321

Brand: STEMCELL Technologies 78004.1

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This item is not returnable. View return policy

Description

Bone morphogenetic protein 2

  • Bone morphogenetic protein 2 (BMP-2) is a member of the transforming growth factor beta (TGF-β) superfamily
  • BMP-2 is a disulfide-linked homodimer, acts as a ligand for complexes of type I and II BMP receptors, and primarily activates SMAD1/5/8 signaling (Nohe et al.) BMP-2 is a potent differentiation factor and directs human pluripotent stem cells (hPSCs) towards various cell types including extra-embryonic endoderm, mesenchymal cells, and chondrocytes (Pera et al.) Although BMP-2 expression is low in healthy cartilage, its expression is upregulated at the site of cartilage damage (Blaney Davidson et al.) BMP-2 induces bone and cartilage formation in vitro and is able to induce chondrogenesis in human mesenchymal stem cells (Schmitt et al.)

Specifications

Name BDA2, BMP-2A, BMP2, Bone morphogenetic protein 2A
Quantity 100 μg
Cell Type Endoderm, PSC-Derived; Hematopoietic Stem and Progenitor Cells; Mesoderm, PSC-Derived; Pluripotent Stem Cells
Purity or Quality Grade ≥95%
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