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STEMCELL Technologies Human Recombinant Noggin
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Quantity:
10 μg
1000 μg
50 μg
Unit Size:
1000µg
10µg
50µg
Description
- Noggin binds to and antagonizes bone morphogenetic protein (BMP) ligands of the transforming growth factor beta (TGF-β) family
- Noggin supports maintenance of undifferentiated human embryonic stem cells in vitro, and can be used to prevent spontaneous differentiation in the short term (Chaturvedi et al.) Noggin is essential for development of structures derived from ectoderm embryonic somite, skeletal patterning, and neurogenesis in vivo
- It also influences chondrogenesis, osteogenesis, and joint formation (Krause et al.), and promotes dopaminergic differentiation of embryonic stem cells and subsequent survival of dopamine neurons (Chiba et al.)
Specifications
Specifications
| Name | NOG, SYM1, SYNS1, Symphalangism 1 (proximal), Synostoses (multiple) syndrome |
| Quantity | 50 μg |
| Cell Type | Neural Cells, PSC-Derived; Neurons; Pluripotent Stem Cells |
| Purity or Quality Grade | ≥95% |
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