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Invitrogen™ Human SMARCC2 (aa 1095-1157) Control Fragment Recombinant Protein

Product Code. 30200546
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30200546

Brand: Invitrogen™ RP107098

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (95%), Rat (95%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q8TAQ2
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 6601
Name Human SMARCC2 (aa 1095-1157) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 5930405J04Rik; BAF170; BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; CRACC2; DKFZp313D0632; LOC685179; mammalian chromatin remodeling complex BRG1-associated factor 170; Rsc8; similar to SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2; Smarcc2; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein
Common Name SMARCC2
Gene Symbol Smarcc2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence SIIPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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