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Invitrogen™ Human TIM-1 Synthetic Peptide

Product Code. 15206579
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50 μg
Unit Size:
50µg
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15206579 50 μg 50µg
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Product Code. 15206579 Supplier Invitrogen™ Supplier No. PEP0363
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Estimated Shipment: 18-08-2026
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Synthetic Peptide

This peptide corresponds to 16 amino acids near the amino terminus of human TIM-1. PEP-0363 can be used as a blocking peptide with polyclonal antibody PA5-20244.

CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail. The endogenous ligand for CD365 is Tim-4. In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus. The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes. Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity. CD365 has also been implicated in the T cell co-stimulation. CD365 is primarily expressed in epithelial cells. It is also highly expressed in A549, 769-P and Caco-2 and cell lines. CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.
TRUSTED_SUSTAINABILITY

Specifications

Gene ID (Entrez) 26762
Species Human
Purification Method purified
Accession Number Q96D42
Common Name KIM-1
Concentration 200 μg/mL
Content And Storage -20°C
Description Synthetic Peptide
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
For Use With (Application) Blocking Assay, Control
Gene Alias AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Gene Symbol Havcr1
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
Storage Buffer PBS
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