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Invitrogen™ Human Treslin (aa 1378-1473) Control Fragment Recombinant Protein

Product Code. 30200045
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30200045

Brand: Invitrogen™ RP106595

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This item is not returnable. View return policy

Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (44%), Rat (44%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83839 (PA5-83839. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number Q7Z2Z1
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 90381
Name Human Treslin (aa 1378-1473) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias C15orf42; SLD3; TICRR; TOPBP1 interacting checkpoint and replication regulator; TOPBP1-interacting checkpoint and replication regulator; topBP1-interacting replication-stimulating protein; topBP1-interacting, replication-stimulating protein; Treslin
Common Name Treslin
Gene Symbol TICRR
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence PSKVGKRCRKTSDPRRSIVECQPDASATPGVGTADSPAAPTDSRDDQKGLSLSPQSPPERRGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHH
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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