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Invitrogen™ Human YPEL3 (aa 1-99) Control Fragment Recombinant Protein

Product Code. 30201246
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. 30201246

Brand: Invitrogen™ RP101075

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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56490 (PA5-56490. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P61236
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 83719
Name Human YPEL3 (aa 1-99) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias 0610043B10Rik; 1190001G19Rik; FKSG5; Protein yippee-like 3; RGD1564579; small ubiquitinated apoptotic protein; Suap; yippee like 3; yippee-like 3; yippee-like 3 (Drosophila); YPEL3
Common Name YPEL3
Gene Symbol YPEL3
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQK
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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