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Invitrogen™ Human ZMYM2 Synthetic Peptide
Description
This peptide corresponds to 17 amino acids near the amino terminus of human ZMYM2. PEP-1204 can be used as a blocking peptide with polyclonal antibody PA5-21090.
ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain and C-terminal nuclear localization signal (NLS) and an acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT 1, 3 and 5. This fusion protein is an oncogenic protein and is associated with an atypical myeloproliferative disease, peripheral blood eosinophilia and T-cell leukemia/lymphoma.
Specifications
Specifications
| Gene ID (Entrez) | 7750 |
| Species | Human |
| Purification Method | purified |
| Accession Number | Q9UBW7 |
| Common Name | ZMYM2 |
| Concentration | 200 μg/mL |
| Content And Storage | -20°C |
| Description | Synthetic Peptide |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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