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Tocris Bioscience™ I 432

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Quantity:
5 mg
Unit Size:
5mg
Description
I 432 is a TMPRSS2 (transmembrane serine proteinase 2) inhibitor (Ki =0.9 nM). It blocks influenza virus propagation in airway epithelial cells. In IPEC-J2 pig jejunal epithelial cells, I 432 (50 μM) inhibits TMPRSS2 without affecting cell viability after 48 h treatment.
Specifications
Specifications
| Chemical Name or Material | 3-[(2 S)-3-[4-(2-Aminoethyl)-1-piperidinyl]-2-[[(2 ',4 '-dichloro[1,1 '-biphenyl]-3-yl)sulfonyl]amino]-3-oxopropyl]benzenecarboximidamide ditrifluoroacetate |
| CAS | 1268874-09-4 |
| Quantity | 5 mg |
| Target | TMPRSS2 |
| Molecular Formula | C29H33Cl2N5O3S0.2 CF3CO2H |
| Purity | 0.98 |
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