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Tocris Bioscience™ IEM 1460
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Product Code. 30002127
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30002127 10 mg 10mg
18025922 50 mg 50mg
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Product Code. 30002127 Supplier Tocris Bioscience™ Supplier No. 1636/10

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164.90 EUR valid until 2026-03-31
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Description

Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors

Voltage-dependent open-channel blocker of AMPA receptors. Selective for GluR2 subunit-lacking (Ca2+-permeable) receptors over GluA2-containing receptors (IC50 values are 2.6 and 1102 μM, respectively). Selectively blocks fast spiking interneuron but not medium spiny projection neuron in mouse striatum. Also blocks NMDA receptor-mediated currents. Anticonvulsant in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 121034-89-7
Molecular Formula C19H38Br2N2

Specifications

Quantity 10 mg
Formula Weight 454.33
Purity >98%
Molecular Weight (g/mol) 454.335
Chemical Name or Material IEM 1460
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