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Tocris Bioscience™ JNJ 16259685
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Product Code. 18074292
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18074292

Brand: Tocris Bioscience™ 2333/10

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This item is not returnable. View return policy

Description

Highly potent, mGlu1-selective non-competitive antagonist

Sub-nanomolar potent, non-competitive mGlu1 antagonist (Ki = 0.34 nM). Inhibits glutamate-induced Ca2+ response at the human mGlu1 receptor with an IC50 value of 0.55 nM. Selective over mGlu5 (> 400-fold) and displays no activity at mGlu2, mGlu3, mGlu4, mGlu6, AMPA or NMDA receptors (IC50 > 10 μM). Centrally active following systemic administration.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 409345-29-5
Molecular Formula C20H23NO3

Specifications

Quantity 10 mg
Formula Weight 325.41
Purity >98%
Molecular Weight (g/mol) 325.408
Chemical Name or Material JNJ 16259685
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