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Tocris Bioscience™ (+)-JQ1 bump, acid functionalized

Product Code. 18005542
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50 mg
Unit Size:
50mg
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Product Code. 18005542 Supplier Tocris Bioscience™ Supplier No. 7689/50

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Functionalized BET bromodomain ligand; precursor for Tag Degraders

(+)-JQ1 bump, acid functionalized is a BET bromodomain binding analog of (+)-JQ1 (Cat. No. 4499) that selectively binds single point mutant form of Brd4 (Brd4BD2 L387A). Functionalized with a carboxylic acid group to enable onward chemistry. The position of the carboxylic acid group represents an 'exit vector' allowing modification without interfering with compound binding ability.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (R)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid
CAS 2421153-77-5
Quantity 50 mg
Target BRD4
Molecular Formula C21H21ClN4O2S
Purity 98%
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