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Tocris Bioscience™ (+)-JQ1 bump, acid functionalized
Description
(+)-JQ1 bump, acid functionalized is a BET bromodomain binding analog of (+)-JQ1 (Cat. No. 4499) that selectively binds single point mutant form of Brd4 (Brd4BD2 L387A). Functionalized with a carboxylic acid group to enable onward chemistry. The position of the carboxylic acid group represents an 'exit vector' allowing modification without interfering with compound binding ability.
Specifications
Specifications
| Chemical Name or Material | (R)-2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)butanoic acid |
| CAS | 2421153-77-5 |
| Quantity | 50 mg |
| Target | BRD4 |
| Molecular Formula | C21H21ClN4O2S |
| Purity | 98% |
Product Title
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