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Description
Histidine is biosynthesized from ATP, 5-phosphoribosyl-1-pyrophosphate (PRPP), and glutamine. In turn, histidine is degraded to glutamate by histidase, urocanase, and imidazolonepropionase via the formation of urocanate, 4-imidazolone 5-propionate, and N-formiminoglutamate.
- Has been used to study cultures of the human T-lymphoblastic leukemia cell line MOLT-4 to study modulation of apoptosis
- Has been shown to enhance the biosynthesis of lovastatin by cultured Aspergillus terreus
- Utilized as a single nitrogen source to probe swarming in Pseudomonas aeruginosa on agar
Specifications
Specifications
| CAS | 71-00-1 |
| Molecular Formula | C6H9N3O2 |
| MDL Number | MFCD00064315 |
| Synonym | l-histidine, histidine, h-his-oh, glyoxaline-5-alanine, anti-rheuma, l---histidine, istidina, s-histidine, l-histidin |
| Solubility Information | Soluble 50mg/mL in 0.5 M HCl. |
| InChI Key | HNDVDQJCIGZPNO-UHFFFAOYNA-N |
| SMILES | NC(CC1=CN=CN1)C(O)=O |
| IUPAC Name | (2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid |
| Molecular Weight (g/mol) | 155.16 |
| Quantity | 10 g |
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