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L-Proline, 99%, Thermo Scientific Chemicals

Product Code. 11449512
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Quantity:
25 g
100 g
500 g

L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
L-Proline is used as asymmetric catalysts in organic synthesis and asymmetric aldol cyclization. It is involved in the Michael addition of dimethyl malonate to alfa-beta-unsaturated aldehydes. It is a precursor of hydroxyproline in collagen. It is an active component of collagen and involved in the proper functioning of joints and tendons. It finds uses in pharmaceutical, biotechnological applications due to its osmoprotectant property. Further, it is used with ninhydrin in the chromatography.

Solubility
Soluble in water and ethanol. Insoluble in ether, butanol and isopropanol.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 147-85-3
Molecular Formula C5H9NO2
Molecular Weight (g/mol) 115.13
MDL Number MFCD00064318
InChI Key ONIBWKKTOPOVIA-UHFFFAOYNA-N
Synonym l-proline, proline, l---proline, s-pyrrolidine-2-carboxylic acid, 2-pyrrolidinecarboxylic acid, --proline, --s-proline, 2s-pyrrolidine-2-carboxylic acid, prolinum, h-pro-oh
PubChem CID 145742
ChEBI CHEBI:17203
IUPAC Name (2S)-pyrrolidine-2-carboxylic acid
SMILES OC(=O)C1CCCN1

Specifications

Melting Point ∽225°C (decomposition)
Beilstein 80810
Solubility Information Soluble in water and ethanol. Insoluble in ether,butanol and isopropanol.
Formula Weight 115.13
Density 1.36
Quantity 100 g
Sensitivity Hygroscopic
Chemical Name or Material L-Proline

RUO – Research Use Only

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