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Invitrogen™ Human MAPK7 (ERK5), GST Tag Recombinant Protein
Human MAPK7 (ERK5), GST Tag Recombinant Protein
Brand: Invitrogen™ A33362
Additional Details : Weight : 0.04500kg
Description
- This MAPK7 (ERK5) recombinant human protein (full length) was expressed in insect cells
- MAPK7 (ERK5) serine/threonine kinase is a member of the MAP kinase family
- It is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development
- MAPK7 is activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5) and is involved in downstream signaling processes of various receptors
- In response to extracelluar signals, MAPK7 translocates to the cell nucleus where it regulates gene expression by phosphorylating and activating different transcription factors
- Gene deletion of MAPK7 in mice results in defective blood vessel and cardiac development leading to embryonic lethality
- MAPK7 has been shown to be critical for endothelial function and maintenance of blood vessel integrity
- MAPK7 (ERK5) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the Z'-LYTE™ assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_620602 | |
| 114.7 kDa | |
| MAP Kinases | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Full Length, Recombinant, Active |
| Kinase Assay | |
| 1 mg | |
| Full Length | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Insect | |
| Liquid |