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Invitrogen™ Human MAPKAPK2, His Tag Recombinant Protein

Product Code. 11563427
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Quantity:
1 mg
10 μg
Unit Size:
10µg
1mg
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Product Code. 11563427

Brand: Invitrogen™ PV3317

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This item is not returnable. View return policy

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Recombinant, Full Length.

MAPKAPK2 mediates p38 and ERK signaling in vivo. It is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. MAPKAPK2 encodes a member of the Ser/Thr protein kinase family. MAPKAPK2 is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for MAPKAPK2.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P49137
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50mM tris with 50% glycerol, 2mM DTT, 150mM NaCl, 0.05mM EDTA, 0.05% Triton X-100 and no preservative; pH 7.5
Gene ID (Entrez) 9261
Molecular Weight (g/mol) 48.8 kDa
Name Human MAPKAPK2, His Tag
pH Range 7.5
Purification Method Purified
Quantity 10 μg
Storage Requirements -80°C, Avoid Freeze/Thaw Cycles
Regulatory Status RUO
Gene Alias AA960234; MAP kinase-activated protein kinase 2; MAPK activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; Mapkapk2; MAPKAP-K2; MAPKAPK-2; mitogen-activated protein kinase-activated protein kinase 2; MK2; MK-2; Rps6kc1
Common Name MAPKAPK2
Gene Symbol MAPKAPK2
KinaseFamily MAPKAPK Kinase Family
Product Type Protein
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Sequence Full length
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Assay Entry Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
Kinase Group Ser⁄Thr Kinases: CAMK Group
Shipping Condition Dry Ice
System Compatibility LanthaScreen™ Antibody, LanthaScreen™ Substrate, Z'-LYTE™, Omnia™ Bulk Substrate
Target Entry MAPKAPK2
Target Gene mitogen-activated protein kinase-activated protein kinase 2
Expression System E. coli
Protein Family Kinases & Inhibitors
Protein Form Recombinant, Full Length
Form Liquid
Protein Subtype Serine/Threonine Kinases
Research Category Signal Transduction
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