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R&D Systems™ (+)-MK 801 maleate

Product Code. 30001147
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30001147 10 mg 10mg
18782704 50 mg 50mg
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Product Code. 30001147 Supplier R&D Systems™ Supplier No. 0924/10
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Description

A Tocris product, part of R&D Systems. Non-competitive NMDA antagonist; acts at ion channel site

(+)-MK 801 maleate is a high affinity (Ki = 37.2 nM), selective and non-competitive NMDA receptor antagonist. (+)-MK 801 maleate acts by binding to a site located within the NMDA associated ion channel and thus prevents Ca2+ flux. It is an effective anti-ischemic agent in several animal models. (+)-MK 801 maleate increases motor activity in rat models. (+)-MK 801 maleate inhibits proliferation and increases apoptosis in hippocampal neural stem cells (NSCs). (+)-MK 801 maleate induces schizophrenia-like symptoms in rodents.

(-)-enantiomer also available.

TRUSTED_SUSTAINABILITY

Kemiske identifikatorer

CAS 77086-22-7
Molecular Formula C20H19NO4

Tekniske data

Quantity 10 mg
Product Line Tocris
Formula Weight 337.37
Purity >99%
Molecular Weight (g/mol) 337.375
Chemical Name or Material (+)-MK 801 maleate
Produkttitel
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