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  5. Tocris Bioscience™ MU 1700 trihydrochloride

Tocris Bioscience™ MU 1700 trihydrochloride

Product Code. 30306097
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30306097

Brand: Tocris Bioscience™ 8832/10

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This item is not returnable. View return policy

Description

Potent and selective ALK1/2 inhibitor. Brain-penetrant

MU 1700 trihydrochloride is a potent and selective ALK2 and ALK1 inhibitor (IC50 values are 6 nM and 13 nM, respectively in biochemical assays). It is also a potent ALK6 inhibitor (IC50 = 41 nM). It shows selectivity for ALK over >360 other kinases. It shows favorable pharmacokinetic for in vivo use. MU 1700 trihydrochloride is orally bioavailable. It is cell membrane permeable and brain penetrant.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 6-(4-Piperazin-1-ylphenyl)-3-quinolin-4-ylfuro[3,2-b]pyridine trihydrochloride
Quantity 10 mg
Target ALK Inhibitors
Molecular Formula C26H22N4O.3HCl
Purity 0.98
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