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N-Ethylmaleimide, 99+%

Product Code. 11368518
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Product Code. 11368518 Supplier Thermo Scientific Alfa Aesar Supplier No. 040526.03
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CAS: 128-53-0 | C6H7NO2 | 125.127 g/mol

N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+ dependent internucleosomal DNA fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 128-53-0
Molecular Formula C6H7NO2
Molecular Weight (g/mol) 125.127
MDL Number MFCD00005509
InChI Key HDFGOPSGAURCEO-UHFFFAOYSA-N
Synonym n-ethylmaleimide, ethylmaleimide, 1-ethyl-1h-pyrrole-2,5-dione, maleimide, n-ethyl, 1h-pyrrole-2,5-dione, 1-ethyl, maleic acid n-ethylimide, nem, usaf b-121, unii-o3c74acm9v, maleic acid-n-ethylimide
PubChem CID 4362
ChEBI CHEBI:44485
IUPAC Name 1-ethylpyrrole-2,5-dione
SMILES CCN1C(=O)C=CC1=O

Specifications

Melting Point 43°C to 46°C
Boiling Point 209°C to 211°C
Flash Point 73°C (163°F)
Assay Percent Range >99+%
Quantity 1 g
Beilstein 112448
Sensitivity Light sensitive
Solubility Information Soluble in ethanol,water,chloroform,methanol and toluene.
Formula Weight 125.13
Physical Form Crystalline
Chemical Name or Material N-Ethylmaleimide
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Identifiant produit
  • N-Ethylmaleimide
Mention d'avertissement
  • Danger
Catégorie de danger
  • Acute toxicity Category 2
  • Acute toxicity Category 3
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
  • Skin sensitiser Category 1
Mention de danger
  • H300-Fatal if swallowed.
  • H311-Toxic in contact with skin.
  • H314-Causes severe skin burns and eye damage.
  • H317-May cause an allergic skin reaction.
  • H318-Causes serious eye damage.
Conseils de prudence
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
Informations supplémentaires
  • MIXTURE LIST-Contain: Maleic acid N-ethylimide

RUO – Research Use Only

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