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N-Hydroxysuccinimide, 98+%

Product Code. 11494063
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Product Code. Quantity unitSize
11494063 25 g 25g
11404073 100 g 100g
11414073 500 g 500g
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Product Code. 11494063

Brand: Thermo Scientific Alfa Aesar A10312.14

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Description

CAS: 6066-82-6 | C4H5NO3 | 115.088 g/mol

N-Hydroxysuccinimide is used for improved amidations in the carbodiimide method. It is also used to activate a carboxyl group and reacts with amine to form amide. It is involved in the preparation of N-hydroxymaleimide-styrene copolymer. Further, it finds use in analytical chemistry. As an additive, it is used in the carbodiimide method for improved amidations and peptide couplings.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysuccinimide is used for improved amidations in the carbodiimide method. It is also used to activate a carboxyl group and reacts with amine to form amide. It is involved in the preparation of N-hydroxymaleimide-styrene copolymer. Further, it finds use in analytical chemistry. As an additive, it is used in the carbodiimide method for improved amidations and peptide couplings.

Solubility
Soluble in water, dimethyl formamide, alcohols and ethyl acetate. Insoluble in cold ether.

Notes
Hygroscopic. Moisture sensitive. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides and strong bases. Store in a cool place.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 6066-82-6
Molecular Formula C4H5NO3
Molecular Weight (g/mol) 115.088
MDL Number MFCD00005516
InChI Key NQTADLQHYWFPDB-UHFFFAOYSA-N
Synonym n-hydroxysuccinimide, hosu, 1-hydroxysuccinimide, 2,5-pyrrolidinedione, 1-hydroxy, 1-hydroxy-2,5-pyrrolidinedione, succinimide, n-hydroxy, n-hydroxysuccinimde, n-hydroxysuccinimid, unii-mje3791m4t, ccris 2604
PubChem CID 80170
IUPAC Name 1-hydroxypyrrolidine-2,5-dione
SMILES C1CC(=O)N(C1=O)O

Specifications

Melting Point 94°C to 99°C
Assay Percent Range >98%
Quantity 25 g
Beilstein 113913
Sensitivity Hygroscopic
Solubility Information Soluble in water,dimethyl formamide,alcohols and ethyl acetate. Insoluble in cold ether.
Formula Weight 115.09
Percent Purity ≥98%
Chemical Name or Material N-Hydroxysuccinimide

Safety and Handling

compliance-icons
Product Identifier
  • N-Hydroxysuccinimide
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
 Supplemental information
  • MIXTURE LIST-Contains : N-Hydroxysuccinimide
SDS

RUO – Research Use Only

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