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Nicotinamide, MedChemExpress

Product Code. p-200096714
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Quantity:
1 g
5 g
Unit Size:
1g
5g
Product Code. Quantity unitSize
16492059 1 g 1g
16480788 5 g 5g
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Product Code. 16492059

Brand: Medchem Express HYB0150

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Description

MedChemExpress Nicotinamide is a form of vitamin B3 or niacin that inhibits sirtuin 2 (SIRT2) activity in vitro, with an EC50 of 2 μM. Nicotinamide inhibits up to 90% melanoma cell number and increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma.

Nicotinamide is a form of vitamin B3 or niacin that inhibits sirtuin 2 (SIRT2) activity in vitro, with an EC50 of 2 μM. Nicotinamide inhibits up to 90% melanoma cell number and increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibts tumor growth in vivo and improves survival of melanoma-bearing mice, which can be used for the research of skin cancers such as melanoma.

Specifications

Chemical Name or Material Nicotinamide
CAS 98-92-0
Color White
Purity Grade Notes Research
Molecular Formula C6H6N2O
Quantity 1 g
Synonym Niacinamide Nicotinic acid amide
Solubility Information DMSO : 50 mg/mL (409.43 mM; Need ultrasonic) ∣H2O : ≥ 50 mg/mL (409.43 mM)
SMILES O=C(C1=CC=CN=C1)N
Molecular Weight (g/mol) 122.12
Formula Weight 122.12
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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