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STEMCELL Technologies Paclitaxel

Product Code. 17150202
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100 mg
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Product Code. 17150202 Supplier STEMCELL Technologies Supplier No. 73312

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Description

Inhibitor of microtubule formation

  • Paclitaxel is a diterpene alkaloid originally isolated from the bark of the Pacific Yew tree (Taxus brevifolia)
  • It binds to and stabilizes microtubules, preventing their reorganization during cell division, which leads to cell cycle arrest
  • Paclitaxel has antitumorigenic properties and has been used as a chemotherapeutic compound (Rowinsky et al.) Many pathways have been implicated in Paclitaxel-induced apoptosis, including c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK), p38 mitogen-activated protein kinase (MAPK), and protein kinase A (PKA; Wang et al.; Reshkin et al.)

Specifications

CAS 33069-62-4
Synonym NSC 125973
Quantity 25 mg
Molecular Formula C47H51NO14
Purity ≥98%
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