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DiscoverX PathHunter™ U2OS NF-KB Pathway Reporter Cell Line

Product Code. 17334429
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17334429

Brand: DiscoverX 931157C3

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This item is not returnable. View return policy

Description

The PathHunter™ U2OS NF-kB Pathway Reporter Cell Line measures NF-kB pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS NF-kB Pathway Reporter Cell Line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting the NFkB pathway. This cell line enables assessment of NFkB pathway stimulation based on changes in the expression of a NFkB response element-driven reporter protein. This product uses EFC technology. The included cell line expresses PL-tagged reporter protein under the control of a NFkB pathway-inducible transcriptional response element. Pathway activation induces expression of the PL-tagged protein, allowing detection of EFC signal upon addition of EA-containing detection reagent. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Transcriptional Reporter
Cell Line U2OS
For Use With (Application) Cell Lines
Primary Agonist CD40L
Quantity 2 Vials
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