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Tocris Bioscience™ PD 98059
MEK inhibitor
Brand: Tocris Bioscience™ 1213/10
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Description
PD 98059 is an inhibitor of mitogen-activated protein kinase kinase (MKK/ MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). Inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Enhances embryonic stem cell self-renewal.Specifications
| 98% | |
| 167869-21-8 | |
| 10 mg |
| 2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one | |
| Room Temperature |
Product Title
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