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  6. Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI) Acylation Reagents

Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI) Acylation Reagents

Product Code. 11747067 Shop All Thermo Scientific Products
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Standard Components:
TFAI
Unit Size:
10mL
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Product Code. 11747067

Brand: Thermo Scientific™ TS48882

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Description

Conduct acylation of hydroxyl groups and primary and secondary amines with the Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI).

Conduct acylation of hydroxyl groups and primary and secondary amines with the Thermo Scientific™ Perfluoroacylimidazoles (TFAI and HFBI). Compared to acid chlorides and anhydrides, the reactions of fluorinated acylimidazoles are smooth and quantitative, and produce no acid byproducts. The principal byproduct is imidazole, which is relatively inert. The volatile and stable fluoroacyl derivatives are ideal for FID and electron-capture detection (ECD) techniques.

Applications

Used in bifunctional derivatization schemes and in exchange reactions in which TMS derivatives are converted to HFB derivatives.

Hydroxyl groups of catecholamines are derivatized with TMSI, followed by conversion of the amines to acylamides with HFBI.

Tryptamine and metabolites present in spinal fluid have been analyzed by ECD using HFBI.

TRUSTED_SUSTAINABILITY

Specifications

For Use With FID, ECD
Hazards Corrosive, Flammable
Storage 2°C to 8°C
Quantity 10 x 1 mL Ampules
Standard Components TFAI
Standard Concentration 98 to 100%
Item Description TFAI; 10 x 1 mL ampules

For Research Use Only. Not for use in diagnostic procedures.

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