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Thermo Scientific™ pH Gradient Buffer Concentrates

Product Code. 15145624
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Description:
CX-1 pH Gradient Buffer A
CX-1 pH Gradient Buffer B
CX-1 pH Gradient Buffer Kit, Buffer A + Buffer B
CX-1 pH Gradient High Resolution Kit, Buffer A + Buffer B
CX-1 pH Gradient High Throughput Kit, Buffer A + Buffer B
CX-1 pH Gradient Starter Kit, Buffer A + Buffer B
Quantity:
125 mL
125 mL + 125 mL
250 mL
250 mL + 250 mL
500 mL
Unit Size:
125mL
250mL
500mL
Product Code. Description Quantity unitSize
15145624 CX-1 pH Gradient Buffer A 250 mL 250mL
15125624 CX-1 pH Gradient Buffer A 125 mL 125mL
15135624 CX-1 pH Gradient Buffer B 125 mL 125mL
15165624 CX-1 pH Gradient Buffer Kit, Buffer A + Buffer B 125 mL + 125 mL 125mL
15155624 CX-1 pH Gradient Buffer B 250 mL 250mL
15121206 CX-1 pH Gradient Buffer Kit, Buffer A + Buffer B 250 mL + 250 mL 250mL
15870452 CX-1 pH Gradient Buffer A 500 mL 500mL
15880452 CX-1 pH Gradient Buffer B 500 mL 500mL
15195624 CX-1 pH Gradient Starter Kit, Buffer A + Buffer B 125 mL + 125 mL 125mL
15185624 CX-1 pH Gradient High Throughput Kit, Buffer A + Buffer B 125 mL + 125 mL 125mL
15105634 CX-1 pH Gradient High Resolution Kit, Buffer A + Buffer B 125 mL + 125 mL 125mL
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This item is not returnable. View return policy

Product Code. 15145624

Brand: Thermo Scientific™ 085346

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This item is not returnable. View return policy

Robust reproducible gradients that are applicable to a wide range of MAbs and ready to use with existing LC columns and systems, without the need to formulate mobile phases.

Obtain fast and highly robust, reproducible HPLC gradients using Thermo Scientific™ CX-1 pH Gradient Buffers. Simple to optimize and easily automated, these buffers are applicable for HPLC separation of the majority of monoclonal antibody (mAb) biotherapeutics drugs. CX-1 pH Gradient Buffers are ready to use with existing HPLC columns without the need to formulate mobile phases. The CX-1 buffers save time in method development, facilitate method transfer to QA/QC for a wide range of mAb charge variants through a generic HPLC-based approach to mAb characterization, and do not require time-consuming mobile phase adjustments.

pH buffer solutions can be used to generate highly reproducible, linear pH gradients in cation exchange chromatography.

  • Robust, reproducible gradients
  • Predict biomolecule pH
  • Simple method optimization
  • Easily automated
  • Applicable to the majority of MAbs

Unlike traditional cation exchange chromatography using salt gradients, it is possible to predict the pH and the expected retention of the charge variants and use a narrow pH range to get a higher resolution separation.

TRUSTED_SUSTAINABILITY

Specifications

Description CX-1 pH Gradient Buffer A
For Use With (Equipment) LC Columns and Systems
Type CX-1 pH Gradient Buffer A
Volume (Metric) 250 mL
pH 5.6
Quantity 250 mL
Standard Concentration 10X
Product Line Thermo Scientific
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Product Identifier
  • buffer A (pH 5.6)
Signal Word
  • Warning
Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
Precautionary Statement
  • P264-Wash thoroughly after handling.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P362+P364-Take off contaminated clothing and wash it before reuse.
Supplemental information
  • MIXTURE LIST-Contains : 2-(N-Morpholino)ethanesulfonic acid (MES), 3-(N-Morpholino)propanesulphonic acid(MOPS), N-[Tris(hyd
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