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Thermo Scientific™ Pierce™ DSP, No-Weigh™ Format

Product Code. 10731945 Shop All Thermo Scientific Products
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Product Code. 10731945 Supplier Thermo Scientific™ Supplier No. 22585
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Description

Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.

Thermo Scientific™ Pierce DSP Crosslinker (Lomant's Reagent) is an amine-reactive crosslinker with NHS-ester reactive ends and a cleavable disulfide bond in its spacer arm.

Highlights:

  • Cleavable by reducing agents
  • Membrane-permeable
  • Acylate in aqueous or organic media within two minutes at room temperature
  • Four- to five-hour half-life of ester at pH 7.0
  • Reactive groups: NHS ester (homobifunctional)
  • Reactive toward: amino groups
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Amine
Cleavable By Thiols
Description DSP
Molecular Weight (g/mol) 404.42
PEGylated No
Spacer Arm Length 12.0 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Yes
Shipping Condition Ambient
Product Line Pierce
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety NHS Ester
Spacer Medium (10 to 30 Å)
Form Powder
Quantity 1 g
Solubility DMF, DMSO
Format Standard, Single-use, Premium-grade
Water Soluble No
Product Type Crosslinker
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Safety and Handling

compliance-icons
Product Identifier
  • DSP (dithiobis(succinimidyl propionate)), Lomant's Reagent
 Signal Word
  • Warning
 Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
 Precautionary Statement
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P337+P313-If eye irritation persists: Get medical advice/attention.
  • P403+P233-Store in a well-ventilated place. Keep container tightly closed.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contain: disuccinimido dithiobispropionate

For Research Use Only. Not for use in diagnostic procedures.

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