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3M™ Polisher ST

Product Code. 17315423
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Diameter (Metric):
4.3 cm
Unit Size:
Pack of 4
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Product Code. Diameter (Metric) unitSize
17315423 4.3 cm Pack of 4
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Product Code. 17315423 Supplier 3M™ Supplier No. 7100228760

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Description

The Polisher ST is a single-use anion exchange (AEX) product intended to reduce host cell protein, viruses, and other negatively charged contaminants in biopharmaceutical process streams.

The 3M™ Polisher ST is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The synthetic, hybrid purifier contains two complementary AEX-functional media: a quaternary ammonium ('Q') functional nonwoven and a guanidinium-functional membrane.

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product's AEX capacity for HCP and virus reduction. Guanidinium functionalized membrane downstream of the functionalized nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged, naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.

Specifications

Disposable Single-use
Material Polypropylene
Material (Membrane) Polyamide
Filtration Area 1 cm2
Flow Rate 1 mL/min.
Inlet Style Luer Lock
No. per Case 4
Outlet Style Luer Lock
Pressure Rating 1.4 bar
Temperature (English) Operating 104°F
Temperature (Metric) Operating 40°C
Height (English) 1.9 in.
Height (Metric) 4.8 cm
Diameter (English) 1.7 in.
Diameter (Metric) 4.3 cm
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