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Eurofins DiscoverX PRKX Protein, Active

Product Code. 17360544
Encompass_Preferred
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17360544

Brand: Eurofins DiscoverX 14677

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This item is not returnable. View return policy

Description

Active, N-terminal 6His-tagged, recombinant, full length, human PRKX, for use in Kinase Assays.

PRKX (Protein Kinase X-Linked) is regulated by and mediating cAMP signaling in cells. It acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. It also regulates myeloid cell differentiation through SMAD6 phosphorylation. In addition, PRKX is involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis, and slso involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.

GenBank NM_005044

Specifications

Formulation mg/mL of enzyme in 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Molecular Weight (g/mol) 44.7 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Full-length
Purity or Quality Grade ≥73%
Protein PrKX, active
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