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Tocris Bioscience™ PX 12
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Product Code. 18015872
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18015872

Brand: Tocris Bioscience™ 2954/10

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This item is not returnable. View return policy

Description

Thioredoxin-1 inhibitor

Thioredoxin-1 (Trx-1) inhibitor; irreversibly inactivates Trx-1 as a substrate for reduction by thioredoxin reductase (TR); competitively inhibits the reduction of Trx-1 by TR (Ki = 30.8 μM). Attenuates expression of HIF-1α, VEGF and iNOS (IC50 values are 7.2, 10.4 and 18.1 μM respectively). Exhibits antitumor activity; directly inhibits tubulin in vitro and decreases tumor microvessel density in vivo.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 141400-58-0
Molecular Formula C7H12N2S2

Specifications

Quantity 10 mg
Formula Weight 188.31
Purity >99%
Molecular Weight (g/mol) 188.31
Chemical Name or Material PX 12
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