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Tocris Bioscience™ R 268712
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Product Code. 18729228
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18729228

Brand: Tocris Bioscience™ 5288/10

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This item is not returnable. View return policy

Description

Potent and selective inhibitor of TGF-βRI

R 268712 is a potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM). Exhibits ∽5000-fold selectivity over p38 MAPK. Suppresses development of renal fibrosis in a unilateral ureteral obstruction model. Also reduces proteinuria, glomerulosclerosis and improves renal function in an anti-Thy1 glomerulonephritis model. Orally bioavailable.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type R 268712
Purity >98%
Molecular Weight (g/mol) 363.39
Inhibitors R 268712

For Research Use Only

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