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  5. Tocris Bioscience™ VU 0422288

Tocris Bioscience™ VU 0422288
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Product Code. 18756499
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Product Code. 18756499 Supplier Tocris Bioscience™ Supplier No. 5378/10

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Description

Selective group III mGlu positive allosteric modulator

VU 0422288 is a group III mGlu receptor positive allosteric modulator (EC50 values are 108, 125 and 146 nM for mGlu4, mGlu8 and mGlu7 respectively). Exhibits selectivity over a panel of 68 other GPCRs, ion channels and transporters. Potentiates mGlu7-mediated reductions in excitatory post synaptic potentials in hippocampal slices.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material VU 0422288
CAS 1630936-95-6
Synonym N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide
Quantity 10 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C17H11Cl2N3O2
Formula Weight 360.19
Physical Form Solid
Product Type Bioactive Small Molecule
Purity >98%

Research Use Only. Not For Human or Veterinary Use

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