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DiscoverX RBL-2H3 MRGPRX1 Gq Cell Line

Product Code. 17334749
Encompass
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Quantity:
2 Vials
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17334749

Brand: DiscoverX 951019C11

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This item is not returnable. View return policy

Description

The RBL-2H3 MRGPRX1 Gq Cell Line measures MRGPRX1 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.

The MRGPRX1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. BAM (8-22)) based activation of MRGPRX1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRX1 , a naturally Gq coupled GPCR. Upon activation of MRGPRX1 , the resulting calcium activity can be fluorescently assayed using the Calcium NoWash PLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Calcium Signaling
Cell Line RBL-2H3
For Use With (Application) Cell Lines
Primary Agonist BAM (8-22)
Quantity 2 Vials
Target Entry MRGPRX1
Accession Number NM_147199
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