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DiscoverX Ready-to-Assay™ NTR1 Neurotensin Receptor Frozen Cells

Product Code. 17345029
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17345029

Brand: DiscoverX HTS034RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ NTR1 Neurotensin Receptor Frozen Cells measure NTSR1 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ NTR1 Neurotensin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. neurotensin) based activation of NTSR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress NTSR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NTSR1 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry NTR1
For Use With (Application) Frozen Cells
Primary Agonist neurotensin
Quantity 2 Vials of Cells
Target Entry NTSR1
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