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DiscoverX Ready-to-Assay™ PAF Platelet Activating Factor Receptor Frozen Cells

Product Code. 17315129
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17315129

Brand: DiscoverX HTS076RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ PAF Platelet Activating Factor Receptor Frozen Cells measure PTAFR (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ PAF Platelet Activating Factor Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. PAF) based activation of PTAFR GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress PTAFR alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of PTAFR , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry PAF
For Use With (Application) Frozen Cells
Primary Agonist PAF
Quantity 2 Vials of Cells
Target Entry PTAFR
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