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DiscoverX Ready-to-Assay™ V 1A Vasopressin Receptor Frozen Cells

Product Code. 17335089
Encompass
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Quantity:
2 Vials of Cells
Unit Size:
2 ampoules
This item is not returnable. View return policy

Product Code. 17335089

Brand: DiscoverX HTS059RTA

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This item is not returnable. View return policy

Description

The Ready-to-Assay™ V 1A Vasopressin Receptor Frozen Cells measure AVPR1A (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

The Ready-to-Assay™ V 1A Vasopressin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. vasopressin) based activation of AVPR1A GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress AVPR1A alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of AVPR1A , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.

Specifications

Assay Entry V1A
For Use With (Application) Frozen Cells
Primary Agonist vasopressin
Quantity 2 Vials of Cells
Target Entry AVPR1A
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